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proteome profiler mouse phospho rtk array kit  (R&D Systems)
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FGFR inhibitor suppresses immune-related <t>proteome</t> signature at 3d post injury. (A) Outline of the experimental design; BAY121 was administered 30 mins after trauma and continued for 3d (25 mg/Kg once daily by oral gavage, vehicle alone as control). Samples were collected 3d post injury. (B) PCA plot of proteomic data shows the separation of TBI-Veh from BAY121-treated samples. (C, D) After modified differential protein expression analysis (FDR <0.05), subsets of upregulated (Red) and downregulated (Blue) proteins with log fold change and individual significance for (D) TBI-Veh compared to Sham–Veh and (D) TBI-BAY121 compared to TBI-Veh (n=5/group). (E) Protein-protein-interaction analysis revealed distinct clustering of downregulated and upregulated proteins in TBI-BAY121 vs TBI Veh; the cluster of downregulated proteins is enriched with immune- and inflammation-related proteins.
Proteome Profiler Mouse Phospho Rtk Array Kit, supplied by R&D Systems, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/proteome profiler mouse phospho rtk array kit/product/R&D Systems
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proteome profiler mouse phospho rtk array kit - by Bioz Stars, 2026-03
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human phospho-rtk array kit  (R&D Systems Hematology)
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FGFR inhibitor suppresses immune-related <t>proteome</t> signature at 3d post injury. (A) Outline of the experimental design; BAY121 was administered 30 mins after trauma and continued for 3d (25 mg/Kg once daily by oral gavage, vehicle alone as control). Samples were collected 3d post injury. (B) PCA plot of proteomic data shows the separation of TBI-Veh from BAY121-treated samples. (C, D) After modified differential protein expression analysis (FDR <0.05), subsets of upregulated (Red) and downregulated (Blue) proteins with log fold change and individual significance for (D) TBI-Veh compared to Sham–Veh and (D) TBI-BAY121 compared to TBI-Veh (n=5/group). (E) Protein-protein-interaction analysis revealed distinct clustering of downregulated and upregulated proteins in TBI-BAY121 vs TBI Veh; the cluster of downregulated proteins is enriched with immune- and inflammation-related proteins.
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https://www.bioz.com/result/human phospho-rtk array kit/product/R&D Systems Hematology
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human phospho-rtk array kits  (R&D Systems Hematology)
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R&D Systems Hematology human phospho-rtk array kits
FGFR inhibitor suppresses immune-related <t>proteome</t> signature at 3d post injury. (A) Outline of the experimental design; BAY121 was administered 30 mins after trauma and continued for 3d (25 mg/Kg once daily by oral gavage, vehicle alone as control). Samples were collected 3d post injury. (B) PCA plot of proteomic data shows the separation of TBI-Veh from BAY121-treated samples. (C, D) After modified differential protein expression analysis (FDR <0.05), subsets of upregulated (Red) and downregulated (Blue) proteins with log fold change and individual significance for (D) TBI-Veh compared to Sham–Veh and (D) TBI-BAY121 compared to TBI-Veh (n=5/group). (E) Protein-protein-interaction analysis revealed distinct clustering of downregulated and upregulated proteins in TBI-BAY121 vs TBI Veh; the cluster of downregulated proteins is enriched with immune- and inflammation-related proteins.
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https://www.bioz.com/result/human phospho-rtk array kits/product/R&D Systems Hematology
Average 90 stars, based on 1 article reviews
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FGFR inhibitor suppresses immune-related <t>proteome</t> signature at 3d post injury. (A) Outline of the experimental design; BAY121 was administered 30 mins after trauma and continued for 3d (25 mg/Kg once daily by oral gavage, vehicle alone as control). Samples were collected 3d post injury. (B) PCA plot of proteomic data shows the separation of TBI-Veh from BAY121-treated samples. (C, D) After modified differential protein expression analysis (FDR <0.05), subsets of upregulated (Red) and downregulated (Blue) proteins with log fold change and individual significance for (D) TBI-Veh compared to Sham–Veh and (D) TBI-BAY121 compared to TBI-Veh (n=5/group). (E) Protein-protein-interaction analysis revealed distinct clustering of downregulated and upregulated proteins in TBI-BAY121 vs TBI Veh; the cluster of downregulated proteins is enriched with immune- and inflammation-related proteins.
Systems Cat Ary001b, supplied by R&D Systems, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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proteome profiler human phospho rtk array kit  (R&D Systems)
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FGFR inhibitor suppresses immune-related <t>proteome</t> signature at 3d post injury. (A) Outline of the experimental design; BAY121 was administered 30 mins after trauma and continued for 3d (25 mg/Kg once daily by oral gavage, vehicle alone as control). Samples were collected 3d post injury. (B) PCA plot of proteomic data shows the separation of TBI-Veh from BAY121-treated samples. (C, D) After modified differential protein expression analysis (FDR <0.05), subsets of upregulated (Red) and downregulated (Blue) proteins with log fold change and individual significance for (D) TBI-Veh compared to Sham–Veh and (D) TBI-BAY121 compared to TBI-Veh (n=5/group). (E) Protein-protein-interaction analysis revealed distinct clustering of downregulated and upregulated proteins in TBI-BAY121 vs TBI Veh; the cluster of downregulated proteins is enriched with immune- and inflammation-related proteins.
Proteome Profiler Human Phospho Rtk Array Kit, supplied by R&D Systems, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/proteome profiler human phospho rtk array kit/product/R&D Systems
Average 95 stars, based on 1 article reviews
proteome profiler human phospho rtk array kit - by Bioz Stars, 2026-03
95/100 stars
  Buy from Supplier
human phospho receptor tyrosine kinase array  (R&D Systems)
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R&D Systems human phospho receptor tyrosine kinase array
FGFR inhibitor suppresses immune-related <t>proteome</t> signature at 3d post injury. (A) Outline of the experimental design; BAY121 was administered 30 mins after trauma and continued for 3d (25 mg/Kg once daily by oral gavage, vehicle alone as control). Samples were collected 3d post injury. (B) PCA plot of proteomic data shows the separation of TBI-Veh from BAY121-treated samples. (C, D) After modified differential protein expression analysis (FDR <0.05), subsets of upregulated (Red) and downregulated (Blue) proteins with log fold change and individual significance for (D) TBI-Veh compared to Sham–Veh and (D) TBI-BAY121 compared to TBI-Veh (n=5/group). (E) Protein-protein-interaction analysis revealed distinct clustering of downregulated and upregulated proteins in TBI-BAY121 vs TBI Veh; the cluster of downregulated proteins is enriched with immune- and inflammation-related proteins.
Human Phospho Receptor Tyrosine Kinase Array, supplied by R&D Systems, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/human phospho receptor tyrosine kinase array/product/R&D Systems
Average 95 stars, based on 1 article reviews
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FGFR inhibitor suppresses immune-related proteome signature at 3d post injury. (A) Outline of the experimental design; BAY121 was administered 30 mins after trauma and continued for 3d (25 mg/Kg once daily by oral gavage, vehicle alone as control). Samples were collected 3d post injury. (B) PCA plot of proteomic data shows the separation of TBI-Veh from BAY121-treated samples. (C, D) After modified differential protein expression analysis (FDR <0.05), subsets of upregulated (Red) and downregulated (Blue) proteins with log fold change and individual significance for (D) TBI-Veh compared to Sham–Veh and (D) TBI-BAY121 compared to TBI-Veh (n=5/group). (E) Protein-protein-interaction analysis revealed distinct clustering of downregulated and upregulated proteins in TBI-BAY121 vs TBI Veh; the cluster of downregulated proteins is enriched with immune- and inflammation-related proteins.

Journal: Frontiers in Immunology

Article Title: The FGFR inhibitor Rogaratinib reduces microglia reactivity and synaptic loss in TBI

doi: 10.3389/fimmu.2024.1443940

Figure Lengend Snippet: FGFR inhibitor suppresses immune-related proteome signature at 3d post injury. (A) Outline of the experimental design; BAY121 was administered 30 mins after trauma and continued for 3d (25 mg/Kg once daily by oral gavage, vehicle alone as control). Samples were collected 3d post injury. (B) PCA plot of proteomic data shows the separation of TBI-Veh from BAY121-treated samples. (C, D) After modified differential protein expression analysis (FDR <0.05), subsets of upregulated (Red) and downregulated (Blue) proteins with log fold change and individual significance for (D) TBI-Veh compared to Sham–Veh and (D) TBI-BAY121 compared to TBI-Veh (n=5/group). (E) Protein-protein-interaction analysis revealed distinct clustering of downregulated and upregulated proteins in TBI-BAY121 vs TBI Veh; the cluster of downregulated proteins is enriched with immune- and inflammation-related proteins.

Article Snippet: Proteome Profiler Mouse Phospho-RTK Array Kit (R&D Systems, Minneapolis) was used to determine the Phospho RTK activation pattern.

Techniques: Control, Modification, Expressing

Prolonged FGFR inhibitor treatment significantly alters the TBI-related proteome profiles at 7d post injury. (A) Outline of the experimental design; BAY121 was administered 30 mins after trauma and continued for 7d (25 mg/Kg/day). Samples were collected 7d post injury. (B) PCA plot shows the substantial separation between TBI groups and groups treated with BAY121. (C, D) After modified differential protein expression analysis (FDR <0.05), subset of significantly upregulated (Red) and downregulated (Blue) proteins with log fold change and individual significance for (C) TBI-Veh vs Sham–Veh and (D) TBI-BAY121 vs TBI-Veh. (E) Protein-protein interaction analysis by STRING reveals three distinct networks affected by prolonged BAY121 treatment, related to protein synthesis proteasomal degradation and inflammation (n=5/group).

Journal: Frontiers in Immunology

Article Title: The FGFR inhibitor Rogaratinib reduces microglia reactivity and synaptic loss in TBI

doi: 10.3389/fimmu.2024.1443940

Figure Lengend Snippet: Prolonged FGFR inhibitor treatment significantly alters the TBI-related proteome profiles at 7d post injury. (A) Outline of the experimental design; BAY121 was administered 30 mins after trauma and continued for 7d (25 mg/Kg/day). Samples were collected 7d post injury. (B) PCA plot shows the substantial separation between TBI groups and groups treated with BAY121. (C, D) After modified differential protein expression analysis (FDR <0.05), subset of significantly upregulated (Red) and downregulated (Blue) proteins with log fold change and individual significance for (C) TBI-Veh vs Sham–Veh and (D) TBI-BAY121 vs TBI-Veh. (E) Protein-protein interaction analysis by STRING reveals three distinct networks affected by prolonged BAY121 treatment, related to protein synthesis proteasomal degradation and inflammation (n=5/group).

Article Snippet: Proteome Profiler Mouse Phospho-RTK Array Kit (R&D Systems, Minneapolis) was used to determine the Phospho RTK activation pattern.

Techniques: Modification, Expressing